Polynucleotides Treatment
Experience the next generation of regenerative skin rejuvenation with our advanced Polynucleotides treatment in Wimbledon. This innovative approach is designed for anyone seeking a proven way to improve skin quality, reduce wrinkles, restore hydration, and achieve a natural, youthful glow—without drastic changes or invasive procedures.
Book nowTREATMENT OVERVIEW
PROCEDURE TIME
45 minutes
PRICE
From £350
ANAESTHESIA
NEEDED
Yes (numbing cream or local anaesthetic)
DISCOMFORT
LEVEL
Moderate
BACK TO WORK
Immediately, you may have multiple small blebs on your face if a needle technique is used
DURATION OF RESULTS
3 to 6 months
FINAL RESULTS
SEEN
After 2 to 4 months
NUMBER OF TREATMENTS
3 to 4
Disclaimer: Please note that the duration of treatments, level of pain experienced during the procedure, and recovery time can vary significantly among individuals. While we aim to provide an estimation based on our clinical experience, factors such as individual pain tolerance, skin sensitivity, and treatment specifics may influence the actual experience. We recommend discussing any concerns or questions regarding these aspects with your healthcare provider prior to undergoing the procedure
Why Choose Damalis Skin Clinic London for Polynucleotides Treatment
Wrinkles are a natural part of ageing, as our production of collagen and elastin slows over time. Combined with sun damage and environmental stress, this leads to fine lines, uneven texture, and a loss of firmness that can make skin appear dull and tired.
At our Wimbledon clinic, we take a modern, medically led approach to anti-ageing and skin care. Under the expert guidance of Dr. Steph, every client receives a detailed consultation where we review your goals, medical history, and skin condition. We capture high-resolution images using the renowned OBSERV 520x skin analysis system at each visit to ensure we are meeting your skin goals.
We’ll then design a personalised plan that uses Polynucleotides—a state-of-the-art biostimulator—to improve skin quality from within. Rather than simply masking signs of ageing, this treatment supports your skin’s natural ability to heal and regenerate.
What Are Polynucleotides?
Polynucleotides are highly purified DNA fragments derived from natural sources, known for their powerful regenerative effects when injected into the skin. Unlike traditional dermal fillers that simply add volume, polynucleotides act as biostimulators—activating the skin’s natural healing processes. They stimulate collagen and elastin production, enhance hydration, improve firmness, and gradually reduce the appearance of fine lines and wrinkles.
The result is healthier, stronger, and more radiant skin with a smoother texture and more even tone. Polynucleotides are especially valued for their subtle, natural-looking outcomes that develop gradually over time—making them ideal for those seeking facial rejuvenation without an “overdone” appearance.
This treatment is versatile and can be used on the face, neck, décolletage, and hands. It’s particularly effective for delicate areas such as Upper and lower eyelids —where it helps reduce dark circles, strengthen the skin, and refresh tired-looking eyes without adding unwanted volume.
How the Treatment Works
During a Polynucleotides session, the solution is carefully injected into targeted areas of the face or neck. Once delivered into the skin, Polynucleotides create a regenerative environment by activating fibroblasts to boost collagen and elastin production. This enhances skin firmness and elasticity while also improving hydration and barrier function.
Additionally, Polynucleotides have anti-inflammatory effects that help reduce redness and irritation, and they support tissue remodeling to smooth uneven texture and tone. Over time, this leads to firmer, more resilient, and youthful skin that glows with health.
Benefits of Polynucleotides
Clients choose Polynucleotides for their ability to reduce the appearance of wrinkles and fine lines while also enhancing elasticity and overall skin health. This treatment improves hydration, making skin look plumper and healthier. It can also fade sun damage, even out tone, and support long-term collagen production for lasting results.
Unlike some treatments that offer quick but artificial results, Polynucleotides work with your body to deliver subtle, natural improvements that maintain your unique features while restoring a youthful glow.
Who is Polynucleotides For?
Polynucleotides are ideal for anyone who wants to address mild to moderate wrinkle concerns or improve overall skin quality without adding volume. They’re excellent for dehydrated, environmentally stressed, or tired-looking skin, and they also work well as part of a preventative skin care strategy for maintaining youthful skin.
Because they work so naturally, Polynucleotides are a great choice for anyone looking to enhance their skin in a subtle but effective way, and they’re also excellent for supporting the results of other cosmetic treatments.
Combining Polynucleotides with Other Treatments
For those seeking even more comprehensive facial rejuvenation, Polynucleotides can be combined with other treatments to achieve optimal results. Many clients choose to pair them with anti-wrinkle injections to relax facial muscles and prevent dynamic wrinkles, or with dermal fillers to restore lost volume and smooth deeper creases.
They also work beautifully alongside chemical peels that refresh the outer layers of the skin or microneedling to further stimulate collagen production. During your consultation, we’ll help you decide on the best combination for your unique needs.are ideal for anyone who wants to address mild to moderate wrinkle concerns or improve overall skin quality without adding volume. They’re excellent for dehydrated, environmentally stressed, or tired-looking skin, and they also work well as part of a preventative skin care strategy for maintaining youthful skin.
Because they work so naturally, Polynucleotides are a great choice for anyone looking to enhance their skin in a subtle but effective way, and they’re also excellent for supporting the results of other cosmetic treatments.
Polynucleotides BEFORE & AFTER
WHAT MAISIE SAYS ABOUT HER TREATMENT
“I went to see Dr Steph for anti-wrinkle treatment in my frown lines, forehead and crow’s feet. As it was my first ever treatment, I was quite nervous — I wanted to look fresher but still natural, and I didn’t want anyone to know I’d had anything done.
Dr Steph really put me at ease. She explained everything clearly and suggested starting gently, with the option to add more at my review if I felt I needed it. That approach made me feel very comfortable.
I couldn’t be happier with the results. No one noticed I’d had treatment, but I looked fresher, my makeup sat better, and I still had natural movement in my face. That was really important to me.
I’ve since been back several times and I always feel I’m in safe hands. I’d recommend Dr Steph to anyone looking for subtle, natural results.”
Polynucleotides Treatment FAQs
Are Polynucleotides treatment safe?
Yes. Polynucleotides are highly purified and biocompatible, with a strong safety record. Treatments are performed under strict medical supervision.
How many sessions will I need?
Most clients see best results after 3-4 sessions spaced about 3 to 4 weeks apart. Maintenance treatments are important for sustained results.
Does it hurt?
Discomfort is minimal. We offer numbing cream to ensure the procedure is as comfortable as possible.
When will I see results?
Gradual improvements appear within a few weeks as collagen production increases. Full results continue to develop over several months.
What concerns does it treat?
This treatment effectively targets fine lines, wrinkles, dehydration, loss of firmness, uneven skin tone, sun damage, and dull or tired-looking skin. It’s also highly effective for improving the appearance of dark under-eye circles and addressing skin laxity on the upper eyelids.
Is there downtime?
Minimal. You might experience mild redness or swelling for 1 to 2 days, but most people return to normal activities immediately.
How is this different from fillers?
Unlike fillers that add volume immediately, Polynucleotides work by stimulating collagen and improving skin quality gradually for subtle, natural results.
Can I combine it with other treatments?
Absolutely. Polynucleotides can be safely combined with anti-wrinkle treatments, fillers, chemical peels and microneedling for comprehensive facial rejuvenation.
Is it suitable for all skin types?
Generally, yes. Most skin types can benefit. Suitability will be confirmed during your consultation.
How do I get started?
Simply book a consultation at our Wimbledon clinic to discuss your goals and design your personalised treatment plan.
